As a healthy bone marrow begins to deteriorate as a result of leukemia, aplastic anemia, lymphoma or osteomyelitis or Due to procedures such as chemotherapy and radiation, the bone marrow of the respective donor must be replaced. This procedure is called bone marrow transplants, where blood stem cells are moved to the brain to produce new blood cells, which in turn helps new brain growth. Most often, bone marrow transplantation is performed in patients with blood cancer or osteomyelitis. Bone marrow transplants can be used to treat a variety of diseases, including – 1. Aplastic anemia, when the formation of new blood vessels in the bone marrow stops. 2. Congenital neutropenia, an inherited disease that causes chronic infections. 3. Bone marrow cancer, including leukemia, lymphoma, and multiple myeloma. 4. Neuroplasty, where “neuro” means nerves, and “blast” means cancer that affects developing or immature cells, mostly in and around the adrenaline glands. Neuroblastoma can also occur in other parts of the body, such as the abdomen, chest, neck, spine. 5. Thalassemia, a genetic vascular system that forces the human body to form hemoglobin in an abnormal way. 6. Herler’s syndrome is a disorder of congenital disorder, it is a rare form of mucopolysaccharidosis type 1, lysosomal storage disorder can cause a wide range of problems that may include skeletal abnormalities, respiratory problems, reduced life expectancy, etc. 7. Sickle cell anemia, a genetic vascular failure that results in red blood cells. 8. Adrenocodistrophy, a genetic abnormality that can destroy myelin in lashes and hyperactivity. 9. Impaired immune deficiency when the body loses the ability to fight infections and diseases effectively. Types of bone marrow transplants (BMT): There are two main types of bone marrow transplant procedures – 1. Autologous BMT 2. Allogeneic BMT In addition to the above, there is another type of bone grafting procedure called haploidentical transplantation. 1. Autologous bone marrow transplantation: During this procedure, the patient’s stem cells are removed from their body before starting high-dose chemotherapy or radiation treatment. Collected stem cells are stored in the freezer. After chemotherapy or radiation surgery, the stem cells will return to the patient’s body to help create normal blood cells. Umbilical Cord Blood Transfusion i Other types of autologous bone marrow transplantation. Umbilical brain blood transfusion is a procedure that involves removing the umbilical cord of a newborn baby right after birth. The collected stem cells are frozen and stored in the patient until transplantation is needed. Since umbilical brain cells are highly immature, there is less need for perfect coincidence. 2. Allogeneic bone marrow transplantation: During this procedure, stem cells were removed from another person, often referred to as donors (preferably the patient’s brother, parent, or close relatives). In most patients, the donor’s genes must match the patient’s gene (at least in part). 3. Haploidentical Transplantation: Donor cells can be used even when the donor is unable to meet the entire complex of criteria with the help of a haploidentical transplant procedure. Therefore, this type of transplant helps the donor pool. The type of procedure used by a bone marrow transplant surgeon depends on a variety of factors, such as the damage caused by age and health during the treatment period /// Our Medical Center


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